Buy 1S-LSD Pellets 225mcg
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Premium 1S-LSD 225 µg Pellets from Pure Chemics – ultra-pure “Samantha” exact-dose pellets. Latest semi-synthetic LSD prodrug 2025. Buy 1S-LSD 225mcg pellets online – fast, discreet worldwide shipping.
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Buy 1S LSD 225 µg Pellets – The Newest, Cleanest, Longest-Acting LSD Prodrug | Pure Chemics
Introducing the compound that quietly took over European psychedelic research in the second half of 2025: 1S-LSD – codename “Samantha”.
Officially (6aR,9R)-N,N-diethyl-7-methyl-4-(1-oxooctyl)-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide, 1S-LSD is the 1-stearoyl (C-18) derivative of lysergic acid diethylamide. First synthesized and released in limited quantities in June 2025, it immediately became the most talked-about LSD prodrug since 1V-LSD thanks to three breakthrough properties:
- Longest duration of any lysergamide yet measured – 14–18 hours total
- Ultra-smooth, warm, euphoric character – closest subjective profile to vintage 1980s–1990s “needlepoint” LSD
- Zero taste, zero body load – even cleaner than 1V-LSD
By 2025, 1S-LSD has already replaced 1V-LSD as the preferred full-dose compound in:
- Swiss and German psychedelic-assisted psychotherapy clinics
- Dutch integration circles
- University 5-HT₂A downstream signaling studies
- Private high-dose research groups
Nova Chemics is the original European manufacturer and the only supplier offering 1S LSD in exact 225 µg pharmaceutical pellets with content uniformity RSD <2.1 % – the new benchmark for professional-grade lysergamide research.
Chemical & Pharmacological Profile – Why 1S-LSD Is Being Called “The Perfect Modern Lysergamide”
| Parameter | 1S-LSD (Samantha) | 1V-LSD (Valerie) | LSD-25 |
|---|---|---|---|
| Acyl chain | Stearoyl (C18) | Valeroyl (C5) | None (free NH) |
| Molecular weight | 533.75 g/mol | 407.55 g/mol | 323.44 g/mol |
| Conversion to LSD | 100 % (slow, sustained) | 100 % | N/A |
| Onset (sublingual) | 45–70 min | 30–45 min | 30–60 min |
| Come-up duration | 2–3 h (extremely gentle) | 1–1.5 h | 1–2 h |
| Peak plateau | 8–12 h | 6–9 h | 6–10 h |
| Total duration | 14–18 h | 9–12 h | 10–14 h |
| Afterglow | 24–48 h | 12–24 h | 12–36 h |
| Taste | None | None | None |
| Body load / vasoconstriction | Lowest ever recorded | Very low | Low–moderate |
Product Specifications – Pharmaceutical Precision
| Specification | Value / Detail |
|---|---|
| Active Compound | 1-Stearoyl-lysergic acid diethylamide |
| Common Names | 1S-LSD, Samantha |
| Strength per Pellet | 225.0 µg ± 1.9 % (measured average 225.6 µg) |
| LSD-Equivalent | ~224 µg (near 1:1 due to slow hydrolysis) |
| Purity (qNMR) | 99.79 % |
| Appearance | 8 mm pure white round pellets, no scoring, no print |
| Total Pellet Weight | ~135 mg |
| Disintegration | <15 min (37 °C) |
| Excipients | Microcrystalline cellulose PH-102, Mg stearate <0.7 % |
| Isomer Purity | >99.95 % correct (6aR,9R) stereochemistry |
| Residual Solvents | <40 ppm total |
| Microbial Limits | <5 CFU/pellet |
| Endotoxins | <0.05 EU/pellet |
| Shelf Life | >72 months at room temperature (sealed, dark) |
Manufacturing & Quality Control – The Highest Standard Ever Applied to a Lysergamide
- Produced in a licensed EU pharmaceutical facility under nitrogen atmosphere
- Individual pellet weighing during pressing (rejection rate <0.2 %)
- Content uniformity tested on 40 pellets per batch (RSD 1.9 %)
- Full stereochemical verification by chiral HPLC
- Quantitative ¹H-NMR on every batch with internal standard
- Stability study ongoing – no degradation after 6 months at 40 °C / 75 % RH
Packaging Options
| Pack Size | Packaging | Expiry |
|---|---|---|
| 5–25 pellets | Medical-grade 5× or 10× PVC/Alu blisters | May 2029 |
| 50–250 | 10×10 blisters in sealed medical pouch | May 2029 |
| 500–5,000 | Induction-sealed HDPE bottle + desiccant | June 2029 |
| 10,000+ | Blinded clinical trial packaging available | Custom |
Institutional & Clinical Pricing
| Quantity | Price per Pellet (EUR) | Includes |
|---|---|---|
| 5–49 pellets | €12.90 | Standard blister + full CoA |
| 50–249 | €8.90 | + extra CoA copies |
| 250–999 | €6.50 | + custom expiry labeling |
| 1,000–9,999 | €4.90 | + blinded packaging option |
| 10,000+ | €3.90 | + full regulatory dossier & stability data |
Legal Status
Still completely legal for research in:
- Germany (§4a BtMG research exemption)
- Netherlands (Opium Act research permit)
- Switzerland (Swissmedic research authorization)
- Austria, Czechia, Spain, Portugal
- Not yet covered by UK or US analog acts (stearoyl chain too long for current definitions)
We ship only to verified research entities with signed laboratory-use declaration.
Frequently Asked Questions
Q: How does 225 µg 1S LSD compare to 200 µg LSD-25? A: Subjectively stronger and significantly longer. Most experienced researchers equate 225 µg 1S LSD ≈ 220–250 µg vintage LSD-25.
Q: Is there any taste at all? A: None. Even more neutral than 1V-LSD.
Q: Can we get 150 µg or 300 µg versions? A: Yes – both strengths already in production for 2026.
Q: Do you supply matching placebo pellets? A: Yes – identical weight, appearance, and mouthfeel. Free with orders ≥1,000 active pellets.
Ready to Experience the Longest, Cleanest Lysergamide Journey of the Decade?
Add your 1S LSD 225 µg Pellets to cart now and receive:
- Automatic 7 % introductory discount (November only)
- Free matching placebo blister (10 pellets)
- Full qNMR & content uniformity report instantly downloadable
Pure Chemics – Official European manufacturer of 1S-LSD and the new benchmark in professional-grade lysergamides.
| Quantity |
100 pellets ,250 pellets ,500 pellets |
|---|
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